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Dr Zimmerman, Dr Lin, and Ms Moehling received a research grant from Sanofi Pasteur Inc . Drs Zimmerman, Nowalk, and Lin received research grant funding from Merck & Co Inc ( 38206 ) and have research funding from Pfizer Inc ( 8201807 ). Dr Reis receives research funding from Pfizer Inc . The other authors declare that they have no conflict of interest.